Single intramuscular dose toxicokinetics of manganese in broiler chicks
نویسندگان
چکیده
منابع مشابه
Manganese toxicokinetics at the blood-brain barrier.
Increased manganese (Mn) use in manufacturing and in gasoline has raised concern about Mn-induced parkinsonism. Previous research indicated carrier-mediated brain entry but did not assess brain efflux. Using in situ rat brain perfusion, we studied influx across the blood-brain barrier (BBB*) of three predominant plasma Mn species available to enter the brain: Mn2+, Mn citrate, and Mn transferri...
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A study was undertaken to assess the hepatotoxic and nephrotoxic potential of ketoprofen in comparison with diclofenac upon short-term intramuscular (i.m.) administration in broiler chickens. Eighteen broiler chickens were randomly divided into 3 groups of 6 birds each. Group I served as the control and received normal saline (0.1 mL, i.m.), group II was the positive control and received diclof...
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OBJECTIVES This study was performed to analyze the toxicity of the test substance, anti-inflammatory pharmacopuncture (AIP), when used as a single intramuscular-dose in 6-week-old, male and female Sprague-Dawley rats and to find the lethal dose. METHODS The experiment was conducted at Biotoxtech according to Good Laboratory Practices. Twenty (20) female and 20 male Spague-Dawley rats were div...
متن کاملComparison of challenge models for determining the colonization dose of Campylobacter jejuni in broiler chicks.
Coprophagous activity is normal among broiler chickens. The purpose of this study was to compare an individually housed chick model (where bird-to-bird coprophagia was prevented) to a group-housed chick model (where bird-to-bird coprophagia was allowed) for determining estimates of the number of Campylobacter jejuni RM1221 necessary to colonize 50% of broiler chicks inoculated (colonization dos...
متن کاملDose titration of FITC-D for optimal measurement of enteric inflammation in broiler chicks.
Traditionally, antibiotic growth promoters (AGP) have been used in foodstock animals to reduce enteric inflammation and maintain intestinal homeostasis, thus improving growth and performance. Due to increasing restrictions regarding the use of AGP however, precise and high throughput enteric inflammation models and markers to search for effective alternatives are urgently needed. In this paper,...
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ژورنال
عنوان ژورنال: Veterinary World
سال: 2012
ISSN: 0972-8988
DOI: 10.5455/vetworld.2012.560-564